The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States under the brand name Benadryl),[a] which acts as a deliriant in...
Benadryl overdose signs include strong drowsiness, confusion or hallucinations, extreme dryness, and fast or irregular heartbeat. What to do in the case of a Benadryl Overdose: CALL 911 right away.
Benadryl is an over-the-counter often taken to alleviate symptoms of allergies and insomnia, but it has abuse potential. Learn more here.The Aftermath of Benadryl Overdose. Consuming more than the recommended dose leads to overdose.

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In overdose, diphenhydramine can cause excessive sleepiness, confusion, hallucinations, fast heartbeat, seizures, and coma. Take Benadryl as directed by a pharmacist or physician to avoid unwanted side effects.
Discover how Benadryl overdose happens, its dangerous symptoms, and available medical treatments. Learn how to use Benadryl safely and avoid toxicity.

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Why do some people misuse Benadryl? Some try it after seeing the Benadryl Challenge on TikTok or other social media, hoping for euphoria. In reality, high doses lead to Benadryl overdose and medical emergencies, not a safe high.